Skip to content
Contact us

SepaBean™ machine L

Scale-up Automated Flash Chromatography System

See the range

If you want to find out more about the SepaBean Flash System Range or to book a demo, please get in touch with Chromatography Direct.

Overview

The SepaBean™ machine L is an advanced system designed for large-scale purification with a high flow rate of up to 1,000 mL/min, providing effortless scalability and user-friendly operation. It allows seamless transitions from lab-scale experiments to pilot-scale production. The anti-static design ensures enhanced safety and reliability, while the optional sample loading module increases productivity by efficiently handling large sample volumes.
 
 
SepaBean machine-L
Optional Sample Loading Module & Fraction Collector
machine-L-accessories
  • Higher Flow Rate & Loading Capacity

    High flow rate (1,000 mL/min) model designed to handle high-volume samples of up to 1 kg in a single run.

  • Wireless Control and Operation

    Allows remote control via mobile devices, ideal for light-sensitive or isolated experiments.

  • Easy Flash Method Development

    Optimises and transfers separation conditions from HPLC and TLC for efficient, scalable purification.

  • Optional ELSD Detector

    Optional ELSD expands detection capabilities to cover a wider range of sample types, including non-UV-active compounds.

dual-piston-pump

Dual-Piston Pump

4-Lines

Four Solvent Lines

50-1000-ml

Maximum Flow Rate (mL/min) 

 

1450-PSI

Pressure Resistance (psi)

 

machine L Specifications

  Specifications
User Interface 4.3 inches screen (≈ 10 cm)
Control Device Wireless operation through iPad®
Flow Rate Range 50 - 1,000 mL/min
Maximum Pressure • Model 1000LP: 150 psi (10.3 bar)
• Model 1000MP: 1,450 psi (99.9 bar)
Detectors • DAD 200 - 400 nm UV Detector
• DAD 200 - 800 nm UV/Vis Detector
• ELSD Universal Detector (optional)
Spectral Display Single, dual, or all-wavelengths
Pumping System High accuracy dual-piston pump
Number of Solvents Four (4) solvents binary with any combinations of two (2) solvents, high pressure mixing
Gradient Types Isocratic, linear, and step gradients
Column Sizes 800 g - 10 Kg
Sample Loading Capacity 8  g - 1 Kg
Certification CE
21-CFR Part 11 Compliance The control software meets FDA requirements for system safety
Collection Module LCD display for intelligent identification of test tube racks
Fraction Collection All, waste, threshold, slope, or time
Fraction Collector Optional collection module, with 8 collection channels
Safety Configuration Intelligent pressure alarm
Sample Injection Optional sample loading pump module, 100 and 200 mL/min options available
Column Holder Suitable for 800 g to 3 kg flash columns, addiotnal column holder for 5 and 10 Kg columns (optional)
Dimensions
(W x D x H)		 33 x 57 x 56 cm cm
(13.0 x 22.4 x 22.0 in)
Weight 40 kg (88 lbs)

SepaBean Small Scale Models

Sepabean-machine-u

SepaBean machine U

Entry-level model designed to handle everyday separation and purification tasks.

Entry Level
SepaBean-Machnie-T

SepaBean machine T

Best-selling model, offering a highly cost-effective solution for efficient chromatography.

Cost Effective (Best Seller)
SepaBean-Standard

SepaBean machine

The standard version featuring a high pressure mixing.

Standard version
SepaBean-Machine-2

SepaBean machine 2

Medium-pressure model with a flow rate up to 300 mL/min and 500 psi (34.5 bar) tolerance.

Medium Pressure

SepaBean Brochure

Download

Application Notes

Application Notes using SepaBean

See All

Want to know more

If you want to find out more about the SepaBean instrument range, please get in touch with Chromatography Direct.